At a high-level campaign fundraiser, up-and-coming Senator Tom Wright becomes violently ill. Vogler pushes House to take Wright’s case and also dangles a new incentive in front of him: deliver a speech on behalf of Vogler’s pharmaceutical company, and save his whole team. While the Senator’s symptoms and tests point to AIDS, a condition which would squash his White House dreams forever, House and the team dig for different answers.

Meanwhile, House gives the speech, but it’s not exactly what Vogler had in mind.